I haven't had too many crashes. 3 in the first 3 hours, and then I unplugged my controller (which I wasn't using anyway) and haven't had a crash since. I think I woke up on the wrong side of the smart, though, because this game is way more difficult than 3 ever was, and I'm only on normal. Everywhere I go there are enemies several levels above me that don't seem to take any damage at all because armor. My only chance at killing anything appears to be tossing dynamite around.
Oh, and I've been trying to play blackjack to make money, since killing things is out of the question. Apparently 5 luck is the equivalent of no luck, since every single time I hit on 12 I get a face card. Taking 5 luck was stupid to begin with, since this is fucking Vegas, but honestly I didn't think the games would be this rigged.
Still, I'm liking this game a lot. Karma is basically meaningless (because the karma system was stupid to begin with) and the reputation thing is cool. Also being able to wear enemy armor so they think you're one of them (although that also means every armor I've got comes with a chance of being shot at when I fast travel to the wrong area). And my companion punches things so hard their limbs come off.
I'm currently working on taking over Vegas. The only difficult part is deciding which of the 5 minor factions hasn't pissed me off enough to kill them. Everyone in the mojave has a fucking attitude problem and as [spoiler]the guy who killed Benny and Mr. House in their own casinos[/spoiler] I feel like I deserve a little more respect than that, even if a group of raiders with pistols can insta-kill me.